@Eoniw there is this from the paper Karl linked
Quote:
Azithromycin appears to act as a lysosomotropic agent, affecting lysosomal traffic and pH [13,14]. A similar mechanism has been proposed for the now controversial hydroxychloroquine [15], which alkalinizes phagolysosomes by inhibiting viral segmentation mediated by pH-dependent proteases, interfering with the fusion process and viral replication. Perhaps it is needed to correctly determine the minimum not toxic effective dose. Possible effects of azithromycin would include interference with ACE2 receptor and decrease virus binding [16], increase of the intra-vesicular pH of endosomes and lysosomes up to around neutrality, thereby inhibiting the lysosomal enzyme activities responsible in virus entry and replication cycle [17].
So although antibiotics don't directly kill viruses it is possible they could have some antiviral effect.
I'm not a doctor but I generally avoid antibiotics unless they are necessary. I wouldn't make it a habit of taking them every time I felt off.