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User Info The Low-Hanging Fruit; entered at 2017-03-04 06:41:42
Posts: 9355
Registered: 2007-06-26 Location: Terra Firma
I would actually argue that metformin shouldn't be part of the insurance plan.

A person is diagnosed as a Type II diabetic when their fasting blood sugar is 126 mg/dl or higher. In a T2D, glucose builds up in the blood because the cells in the body have developed "insulin resistance", whereby it takes more and more insulin to clear glucose from the blood and deposit it in the cells. Metformin helps overcome insulin resistance, thereby forcing more sugar into the various cells of the body.

Now the problem is that insulin resistance is protective. It occurs because the cells are being damaged by constant bombardment of excess glucose. The cells are protecting themselves from this onslaught by reducing the amount of sugar they can accept. High serum glucose is a symptom and not a cause of T2D so using a drug like Metformin to take sugar out of the blood and hide it in the cells is not actually helpful, in fact it's detrimental. Like most drug therapies Metformin concentrates on reducing the symptom of insulin resistance and not the actual cause of T2D, which is the body producing too much insulin due to a poor diet. A few months ago I ran across a study showing there was no benefit in outcomes between T2D's treated with diabetes drugs and those who went w/o treatment. No surprise to me.

It's unfortunate that Type 1 Diabetes and Type 2 Diabetes are both called diabetes because they have two entirely different causes. Type 1 diabetics make no insulin whatsoever and are unable to clear glucose from the blood therefore are benefited by exogenous insulin. Type 2 diabetics make too much insulin which causes insulin resistance which results in high blood glucose but is treated the same T1D, exogenous insulin. Medicine is literally treating a disease caused by too much insulin by giving these people even more insulin. What a bunch of ****tards. Metformin doesn't address the issue of there simply being to much glucose in the body, it just takes that glucose out of the blood and puts it where it still causes damage. Because of drugs like Metformin, a person can have "normal" blood sugar but still be diabetic.
2017-03-04 06:41:42