@Tickerguy,
"The best-fit hypothesis is that there is no way to control manufacturing at-scale when the product causes the body to produce a pathogenic thing via a biological process."

OK, this makes perfect sense to me.
We are all different! Our physiologies have different capacities. People have different vulnerabilities to . . . everything. There is no way to predict for sure who will succumb to a certain disease, or who will survive an extreme situation such as extreme thirst. Look at the snafus with "modeling" (covid and climate). Perhaps some people even have a mutation that prevents them from responding to the code introduced. Whatever.

This assumption that the human body is like an internal-combustion engine and we understand everything about what makes it go---just turn the ignition key---is the same kind of hubris that wants to start "responsibly" discussing climate engineering at COP26. Playing games with the planet's life systems, and with humans' as well.