It's Not All About The Corruption -- Right?
The Market Ticker - Canceled - What 'They' Don't Want Published
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2021-06-07 15:46 by Karl Denninger
in Corruption , 228 references Ignore this thread
It's Not All About The Corruption -- Right?
[Comments enabled]

Naw, it's not the $56,000 price tag that led to approval -- right?

Biogen Inc. shares were on track for their biggest gain on record after the drugmaker released pricing for its recently approved Alzheimer’s drug Aduhelm. 

May I point out that this drug failed one of two controlled trials and was approved under "fast track" authority anyway?

Of course Dr. Siegel thinks this is the best thing since sliced bread.

But.... while there are claims that this drug helps to remove and prevent the proteins in the brain that are linked to Alzheimer's the problem is that when a trial on a drug of this sort fails you have to step back.  Is it worthless or worthwhile?  Nobody really knows nor do we know much of anything about the side effects as they've not been published. Indeed there's plenty of debate over whether the "plaques" seen in Alzheimer's patients is the cause of the brain dysfunction or whether it's a biological result of what causes the dysfunction.  In the latter case the drug will not work since that's not the actual problem, of course.

But what we do know is that this "accelerated approval" will make Biogen a hell of a lot of money whether the drug works or not.

And if you get the side effects?  Sucks to be you, I suppose.

We haven't seen anything like that in the recent past out of the FDA, have we?

Just asking....

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Bodhi
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TPTB have made it in-your-face blatantly obvious that they consider us to be the beta testers for their experimental concoctions.

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It is hopeless doing things for people, it is often very dangerous
indeed to do things at all, and the only thing worth doing for
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Cmoledor
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Akron Ohio
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No shock here. Its all a scam.

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The whole world is one big ****ing scam
Scottl1023
Posts: 33
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NJ
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Slow Joe the Pedo should be the first to sign up for this Jab
Obseedian
Posts: 13926
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Diversitopia
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Since Alzheimers also involves demyelination and there is evidence it might be an autoimmune disorder, trying Ivermectin wouldn't hurt either.

https://multiplesclerosisnewstoday.com/2....
Quote:
A common anti-parasitic agent showed a potential to prevent inflammation and to promote nerve cell recovery remyelination in a mouse model of multiple sclerosis (MS).

By promoting the activity of a receptor called P2X4R that is present in microglial cells immune cells that reside in the brain ivermectin (marketed as Stromectol, or Soolantra) eased the clinical manifestations of experimental autoimmune encephalomyelitis (EAE; an induced autoimmune disease similar to MS in humans).

Specifically, researchers saw evidence suggesting that ivermectin was a potential candidate among currently used drugs to promote the repair of myelin damage, they wrote.

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Abelardlindsey
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Every drug intended to treat and reverse Alzheimer's based on the beta amyloid theory has failed to work. There have been 5 or 6 of these trials. This alone tells me that the beta amyloid is an incomplete explanation for Alzheimer's, if not a complete red herring. The researchers need to discard this theory and move on to something else. Of course that means the have to do WORK!
Craiglong
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Hendersonville
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The thing is this drug seeks to breakup the amyloid plaque but newer research shows that the amyloid is probably not the cause of Alzheimer's. It's more of a symptom and is actually a protective response to the underlying cause which may be many different things. Without root cause resolution Aduhelm is probably wasted money for the patient - a lot of money.
Shadowmask
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Ketones do wonders for reversing early onset dementia and Alzheimer's, but they're free!
Burya_rubenstein
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Give it to Biden.
Steph4liberty
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Raleigh, NC
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Our society has been turned into one where instant gratification is king. Now we're seeing it in pharmaceuticals. Get the approval any way you can and screw any trial that doesn't show what they want it to show. Dust dust under the rug.

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Chiff
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Timberlake Va
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Modern day Fascism at it's finest.
https://twitter.com/VivekGRamaswamy/stat....
Kokobeware
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Saw this earlier today and literally punched a hole through my monitor.

Clinical studies in 2019 failed and the drug was shelved ... or was it. About 6 months later Biogen reemerged with "extra" data suggesting heavy doses of the drug might help reduce symptoms. LMFAO. These people are the worst of humanity. Sick bloodsucking ghouls.
Abelardlindsey
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Quote:
Since Alzheimers also involves demyelination and there is evidence it might be an autoimmune disorder, trying Ivermectin wouldn't hurt either.


Yes. it is a manifestation of autoimmune disorder. I believe much of autoimmune disorder, in turn, is a manifestation of metabolic syndrome. So is type II diabetes. Metabolic syndrome is likely the source of many commonly diagnosed disorders that are considered part of the aging process itself. its all based on mitochondrial dysfunction.

Its all in the mitochondria.
Edwardteach
Posts: 52
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Here be dragons
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BTW, have you seen this yet?

"The Covid-19 pathogen has a genetic footprint that has never been observed in a natural coronavirus."

https://www.wsj.com/amp/articles/the-sci....

In a nutshell, the CGG-CGG sequence, which does not occur in nature, is present in the SARS-CoV2 virus.

This link totally doesn't subvert the WSJ paywall:

https://archive.is/f6iG6

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Tickerguy
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A True American Patriot!
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Yeah @Edwardteach you're a bit new around here. I noted that interesting sequence in early 2020..... and while I did not know there was no other coronavirus with it, what I DID know, since it looked odd, is that it's NOT a configuration found in anything but humans, so there goes the zoonotic thing on an almost-conclusive basis.

That was one of the pillars of my original presumption that it was a Wuhan lab accidental release.

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Cmoledor
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Akron Ohio
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@Tickerguy. You still think this was accidental? Or flat out just on purpose with intentional malice? Im going with intentional and all the bastards running our lives were in on it. Every one.

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The whole world is one big ****ing scam
Jw.
Posts: 166
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Leaving CA
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FDA considers abatement of symptoms for six months to be a cure.

Seems logical that larger doses would be considered "successful" for "curing" Alzheimers...

At 56k a dose it looks like everyone but the patient and those paying medical insurance benefit financially... More so when this **** will be directly billed to Medicare.

Will this be considered experimental (since it is being fast tracked) and side effects not be covered by HC insurance providers?

Big Pharma is out of control. If I recall KD did an article about the number of possible school shooters from SSRI drugs could be as many as 50 or 100 per state based on the number of people on SSRI's and the percentage of those expected to have serious side effects.. Seems if a regular capacity magazine manufacturer can be sued when a private individual shoots someone the manufacturers of these drugs should also be exposed to the same suits when their users shot up schools and malls...

Pay off those DC and you get special privileges it seems...

Just more proof that what we have is not in any shape or form actual Capitalism.

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"Why yes, I am trying to destroy the planet. I want your children to live in the hell they deserve..."
Tickerguy
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@Cmoledor - I don't know but, in truth, it doesn't much matter as all the things that happened afterward were definitely NOT accidents.

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I don't give a flying **** if you're offended.
Susanlauren
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These idiots are determined to destroy science, research and the practice of medicine. There will be secondary consequences and far reaching impact that these greedy bastards can not even begin to understand. Corrupt and rotten to the very core.
Cmoledor
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Akron Ohio
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Understood Karl. Thanks. I value your insights.

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The whole world is one big ****ing scam
Edwardteach
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Here be dragons
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@Tickerguy, yeah I figured you already knew, but I thought I'd throw it out there anyway JIC. The fact that the WSJ is talking about it is interesting nonetheless.

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Know what the chain of command is? It's the chain I go get and beat you with until you understand who's in ruttin command here.
Jc3
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Certainly the big boot on the face "citizens" got for the WuFlu from those in charge was not an accidental lab release. It did allow us to see them in all of the full-blown, power-mad glory though.

Seems nutrition plays a big role vs a failed, retread expensive drug.
Discussion of B12 and other nutrients and brain function are known but no $$$ to be made. Some Beaches want to just milk big $$$$ using fake hopium on the afflicted. Even nicotine has been found to have positive impacts(without the smoked version).

Examples(there are many, don't use google):
B12 https://pubmed.ncbi.nlm.nih.gov/18843658....
Nicotine https://pubmed.ncbi.nlm.nih.gov/10326778....
Tsherry
Posts: 5809
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Spokane WA
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So what's the big deal, right? Boomers will do anything to keep from aging, including killing themselves.

Ponder that.

("Hope I die before I get old")
Heartlander
Posts: 156
Incept: 2021-02-25

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@Obseedian

I wanted to double-check your characterization of Alzheimer's as a demyelination disease, so I looked around a little. Forgive me for doubting you!

https://www.pharmacy.biz/myelin-loss-a-r....

That article, in turn, refers to demyelination in "neuropsychiatric disorders." So I looked around and found a bunch of articles from 2013-14 about demyelination in schizophrenia. Here's one:

https://www.sciencedaily.com/releases/20....

Granted, there are other factors likely at play in schizophrenia and maybe at play in Alzheimer's, but still... anything that could address the loss of myelin in any of these diseases is at least WORTH TRYING -- especially since we know, from decades of use, that ivermectin is one of the safest drugs in the world.

Nothing to do with myelin, but another disease in the long and getting longer list of diseases that might be treated with ivermectin is... CANCER. Did y'all see this paper from last year about that?

https://www.ncbi.nlm.nih.gov/pmc/article....

Is there ANYTHING ivermectin can't do?! I'm only half-joking. What an amazing drug. A gift from heaven, if you ask me.
Txdg00
Posts: 45
Incept: 2020-08-10

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Geez, talk about accelerating the timeline for financial collapse. Any guesses as to the final price paid per year per patient by medicare?

Utter insanity.
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